| SMTK | SmartKem, Inc. - Common Stock | | |
| SMX | SMX (Security Matters) Public Limited Company - Ordinary Shares | | |
| SMXT | Solarmax Technology Inc. - Common Stock | D | |
| SMXWW | SMX (Security Matters) Public Limited Company - Warrant | | |
| SNAL | Snail, Inc. - Class A Common Stock | D | |
| SND | Smart Sand, Inc. - Common Stock | | |
| SNDK | Sandisk Corporation - Common Stock When-Issued | | SP500 |
| SNDL | SNDL Inc. - Common Shares | | |
| SNDX | Syndax Pharmaceuticals, Inc. - Common Stock | | |
| SNES | SenesTech, Inc. - Common Stock | | |
| SNEX | StoneX Group Inc. - Common Stock | | |
| SNFCA | Security National Financial Corporation - Class A Common Stock | | |
| SNGX | Soligenix, Inc. - Common Stock | D | |
| SNOA | Sonoma Pharmaceuticals, Inc. - Common Stock | | |
| SNPS | Synopsys, Inc. - Common Stock | | SP500 |
| SNT | Senstar Technologies Corporation - Common Shares | | |
| SNTG | Sentage Holdings Inc. - Class A Ordinary Shares | | |
| SNTI | Senti Biosciences Holdings, Inc. - Common Stock | D | |
| SNWV | SANUWAVE Health, Inc. - Common Stock | D | |
| SNY | Sanofi - American Depositary Shares | | |
| SOCA | Solarius Capital Acquisition Corp. - Class A Ordinary Share | | |
| SOCAU | Solarius Capital Acquisition Corp. - Units | | |
| SOCAW | Solarius Capital Acquisition Corp. - Warrant | | |
| SOFI | SoFi Technologies, Inc. - Common Stock | | |
| SOGP | Sound Group Inc. - American Depositary Shares | | |
| SOHU | Sohu.com Limited - American Depositary Shares | | |
| SOLS | Solstice Advanced Materials Inc. - Common Stock | | |
| SONM | DNA X, Inc. - Common Stock | D | |
| SONO | Sonos, Inc. - Common Stock | | |
| SOPH | SOPHiA GENETICS SA - Ordinary Shares | | |
| SORA | AsiaStrategy - Ordinary Shares | | |
| SORN | Soren Acquisition Corp. - Class A Ordinary Shares | | |
| SORNU | Soren Acquisition Corp. - Unit | | |
| SORNW | Soren Acquisition Corp. - Warrant | | |
| SOTK | Sono-Tek Corporation - Common Stock | | |
| SOUN | SoundHound AI, Inc. - Class A Common Stock | | |
| SOUNW | SoundHound AI, Inc. - Warrant | | |
| SOWG | Sow Good Inc. - Common Stock | | |
| SPAI | Safe Pro Group Inc. - Common Stock | | |
| SPCB | SuperCom, Ltd. - Ordinary Shares | | |
| SPCX | Space Exploration Technologies Corp. - Class A Common Stock | | |
| SPEG | Silver Pegasus Acquisition Corp - Class A Ordinary Shares | | |
| SPEGR | Silver Pegasus Acquisition Corp - Rights | | |
| SPEGU | Silver Pegasus Acquisition Corp - Unit | | |
| SPFI | South Plains Financial, Inc. - Common Stock | | |
| SPHL | Springview Holdings Ltd - Ordinary shares | | |
| SPOK | Spok Holdings, Inc. - Common Stock | | |
| SPPL | SIMPPLE LTD. - Ordinary Shares | | |
| SPRB | Spruce Biosciences, Inc. - Common Stock | | |
| SPRC | SciSparc Ltd. - Ordinary Shares | | |